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Is Cocklebur Toxic to Cats?

☠️ ToxicSeverity: Severe
✅ Cross-checked against veterinary poison-control guidance · Oct 2026 audit
⚠️ Educational info only. If your pet just chewed something and looks unwell, skip the reading and call your vet or Pet Poison Helpline (US): (855) 764-7661.
Yes, cocklebur is severely toxic to cats. The seeds and sprouting seedlings contain carboxyatractyloside, which causes acute liver failure, seizures and death in untreated animals.

Also known as: Clotbur, Rough Cocklebur, Large Cocklebur · Xanthium strumarium

What makes it toxic

Carboxyatractyloside, concentrated in the seeds and in the cotyledons of young seedlings. It blocks cellular energy production, driving acute liver damage and a dangerous drop in blood sugar.

Warning signs to watch for

Vomiting, lethargy, weakness and loss of appetite within hours, progressing to tremors, seizures, staggering, jaundice, low blood sugar and collapse as the liver fails.

What to do if your cat eats it

Emergency. Go to a vet immediately after any known ingestion of burs, seeds or seedlings — early decontamination, IV support and blood-sugar monitoring are the difference between recovery and liver failure.

Common questions

Are the burs dangerous or just the seeds?

The seed inside the bur carries the toxin, and sprouted seedlings are especially concentrated. The spiny bur itself also injures the mouth and gut, so no part is safe.

Where do cats meet cocklebur?

It grows in disturbed ground, ditches and field edges. Outdoor cats that hunt or forage near farms and vacant lots are the ones most likely to bring back a bur or chew a seedling.

More plants checked for cats

This page is general educational information, not a substitute for professional veterinary advice. Every pet is different — if your animal ate something concerning, contact your veterinarian or a pet poison hotline right away. Checking what your pet can eat? Visit our sister site SafeOrToxic.